- 专利标题： NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST HEPATOCELLULAR CARCINOMA (HCC) AND OTHER CANCERS
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申请号： US15918788申请日： 2018-03-12
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公开(公告)号： US20180207253A1公开(公告)日： 2018-07-26
- 发明人: Toni WEINSCHENK , Andrea MAHR , Jens FRITSCHE , Phillip MUELLER , Anita WIEBE , Sara KUTSCHER
- 申请人： IMMATICS BIOTECHNOLOGIES GMBH
- 优先权： GB1423016.3 20141223; GB1501017.6 20150121
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; G01N33/68 ; C07K14/725 ; A61K38/04 ; C07K7/00 ; C07K7/06 ; C07K7/08 ; C07K14/435 ; A61K35/17 ; C12N15/115 ; C12N5/0783 ; C07K16/18 ; C07K14/74 ; A61K35/12
摘要：
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize the cancer cells in the patient that aberrantly express a peptide consisting of the amino acid sequence of GVYDGEEHSV (SEQ ID NO: 303), in which the peptide is in a complex with an MHC molecule.
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