- 专利标题： FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME
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申请号： US15752000申请日： 2016-08-11
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公开(公告)号： US20180230137A1公开(公告)日： 2018-08-16
- 发明人: Robert Zahler , James E. Vath
- 申请人： Zafgen, Inc.
- 国际申请： PCT/US2016/046511 WO 20160811
- 主分类号： C07D405/14
- IPC分类号： C07D405/14 ; A61K9/00 ; C07D491/107 ; C07D491/048 ; C07D491/08 ; C07D487/08 ; C07D413/14 ; A61P3/04
摘要：
Disclosed herein, in part, are fumagillol compounds and methods of use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making fumagillol compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
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