- 专利标题： SERUM ANTIBODY ASSAY FOR DETERMINING PROTECTION FROM MALARIA, AND PRE-ERYTHROCYTIC SUBUNIT VACCINES
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申请号： US15858560申请日： 2017-12-29
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公开(公告)号： US20180231566A1公开(公告)日： 2018-08-16
- 发明人: Philip FELGNER , Stephen L. HOFFMAN , Robert SEDER , Joseph J. CAMPO, JR.
- 申请人： Sanaria Inc. , Antigen Discovery, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human
- 申请人地址： US MD Rockville US CA Irvine US MD Bethesda
- 专利权人： Sanaria Inc.,Antigen Discovery, Inc.,The United States of America, as represented by the Secretary, Department of Health and Human
- 当前专利权人： Sanaria Inc.,Antigen Discovery, Inc.,The United States of America, as represented by the Secretary, Department of Health and Human
- 当前专利权人地址： US MD Rockville US CA Irvine US MD Bethesda
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; A61K39/015 ; G01N33/569 ; A61K39/00
摘要：
Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.
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