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公开(公告)号:US20180231566A1
公开(公告)日:2018-08-16
申请号:US15858560
申请日:2017-12-29
申请人: Sanaria Inc. , Antigen Discovery, Inc. , The United States of America, as represented by the Secretary, Department of Health and Human
IPC分类号: G01N33/68 , A61K39/015 , G01N33/569 , A61K39/00
CPC分类号: G01N33/6854 , A61K39/015 , A61K2039/521 , A61K2039/522 , A61K2039/54 , G01N33/56905 , G01N2333/445 , G01N2469/20 , Y02A50/412 , Y02A50/58
摘要: Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.