- 专利标题： METHOD FOR PRODUCING EMBRYONIC-LIKE STEM CELLS FROM TICKS (ACARI: IXODIDAE), COMPOSITION, USES THEREOF AND DIAGNOSTIC METHODS
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申请号： US15752140申请日： 2016-08-12
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公开(公告)号： US20180236051A1公开(公告)日： 2018-08-23
- 发明人: Darci Moraes Barros Battesti , Irina Kerkis , Ronaldo Zucatelli Mendonca , Durvanei Augusto Maria , Angelina Cirelli Moraes
- 申请人： BIOTICK PESQUISA E DESENVOLVIMENTO TECNOLÓGICO LTDA , FUNDACÃO BUTANTAN
- 优先权： BR102015019426-9 20150812
- 国际申请： PCT/BR2016/050191 WO 20160812
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C12N1/10 ; C12N1/20 ; G01N33/53 ; C12N5/07 ; A61K35/646 ; A61K39/02
摘要：
The invention refers to a process for the production of a continuous cell line of simile embryo stem cells, such as Amblyomma sculptum (Acari: Ixodidae), known as line IBU/ASE-16 (access number with CNCM: 1-5000) and its uses. More specifically, the invention refers to a process for the production of the line IBU/ASE-16 and their use for obtaining extracts for the production of vaccines and candidate recombinant proteins for biopharmaceuticals and acaricides, production of diagnostic kits for the detection of antigens and/or antibodies for animal and human use, obtaining clones for use in genotyping and use as a substrate for the isolation and culture of pathogens.
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