- 专利标题： A METHOD FOR PRODUCING AND PURIFYING RNA, COMPRISING AT LEAST ONE STEP OF TANGENTIAL FLOW FILTRATION
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申请号： US15580092申请日： 2016-05-30
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公开(公告)号： US20180298372A1公开(公告)日： 2018-10-18
- 发明人: Andreas FUNKNER , Stefanie DORNER , Stefanie SEWING , Johannes KAMM , Norbert BROGHAMMER , Thomas KETTERER , Thorsten MUTZKE
- 申请人： CureVac AG
- 优先权： EPPCT/EP2015/062002 20150529
- 国际申请： PCT/EP2016/062152 WO 20160530
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; B01D61/14 ; B01D71/12 ; G01N30/02
摘要：
The present invention relates to method for producing and purifying RNA comprising the steps of providing DNA encoding the RNA; transcription of the DNA into RNA; and conditioning and/or purifying of the solution comprising transcribed RNA by one or more steps of tangential flow filtration (TFF).
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