发明申请
- 专利标题： THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATMENT OF MUSCLE WASTING DISEASES
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申请号： US15984261申请日： 2018-05-18
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公开(公告)号： US20180303944A1公开(公告)日： 2018-10-25
- 发明人: Oleh Taratula , Canan Schumann , Olena Taratula , Adam W.G. Alani
- 申请人： Oregon State University
- 申请人地址： US OR Corvallis
- 专利权人： Oregon State University
- 当前专利权人： Oregon State University
- 当前专利权人地址： US OR Corvallis
- 主分类号： A61K47/34
- IPC分类号： A61K47/34 ; A61K48/00 ; A61K31/7105 ; C08L77/04 ; A61K9/00
摘要：
mRNA polymer complexes and drug delivery systems are disclosed herein that include a cationic polymer electrostatically complexed to an mRNA molecule that encodes a desired protein. Also disclosed herein are methods of treating as well as methods of slowing the loss of, increasing, and/or maintaining lean muscle mass in a subject, such as using mRNA polymer complexes and drug delivery systems.
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