A multi-hypothesis rate adaptation technique may be performed for one or more wireless multimedia streaming scenarios. Managing a multimedia streaming session may involve sending, by a client, a request for a first portion of content to a server. A response may be received from a proxy. The response may comprise the first portion of content and information associated with a second portion of content available via the proxy. A request may be sent to the proxy for the proxy to deliver the second portion of content to the client. A change in a parameter associated with the multimedia streaming session may be determined based on data received from the proxy. It may be determined to change a rate adaptation. A Wireless Transmit/Receive Unit (WTRU) may be configured to perform the rate adaptation.