- 专利标题: CRYSTALLINE FORMS OF PITAVASTATIN CALCIUM
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申请号: US16053879申请日: 2018-08-03
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公开(公告)号: US20180346425A1公开(公告)日: 2018-12-06
- 发明人: Paul Adriaan Van Der Schaaf , Fritz Blatter , Martin Szelagiewicz , Kai-Uwe Schoening
- 申请人: Nissan Chemical Industries, Ltd.
- 申请人地址: JP Tokyo
- 专利权人: Nissan Chemical Industries, Ltd.
- 当前专利权人: Nissan Chemical Industries, Ltd.
- 当前专利权人地址: JP Tokyo
- 优先权: EP03405080.7 20030212
- 主分类号: C07D215/14
- IPC分类号: C07D215/14
摘要:
The present invention is directed to new crystalline forms of Pitavastatin hemicalcium salt, referred to hereinafter as polymorphic Forms A, B, C, D, E and F, as well as the amorphous form. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and the amorphous form and pharmaceutical compositions comprising these crystalline forms or the amorphous forms.