A compensation pixel circuit, a display panel, a display apparatus, a regional compensation method and a driving method are provided. The compensation pixel circuit includes a compensation driving circuit and a signal acquiring circuit connected with the compensation driving circuit. The compensation driving circuit includes a driving transistor and an organic light-emitting diode. The compensation driving circuit is configured to receive a light-emitting data signal, compensate a threshold voltage of the driving transistor, and drive the organic light-emitting diode to illuminate in accordance with the light-emitting data signal. The signal acquiring circuit is configured to acquire a gate voltage of the driving transistor.