- 专利标题: BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
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申请号: US16134391申请日: 2018-09-18
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公开(公告)号: US20190002564A1公开(公告)日: 2019-01-03
- 发明人: Marina BACAC , Thomas HOFER , Ralf HOSSE , Christiane NEUMANN , Christian KLEIN , Ekkehard MOESSNER , Pablo UMANA , Tina WEINZIERL
- 申请人: Roche Glycart AG
- 优先权: EP13156686.1 20130226
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; C07K16/30
摘要:
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
公开/授权文献
- US10781257B2 Bispecific T cell activating antigen binding molecules 公开/授权日:2020-09-22