A test system and a corresponding method for testing the seal of a glove which is installed in a port of an isolator, including a test disc which can be connected in a hermetically sealed fashion to the port. The glove and test disc define a sealed glove volume which can be placed under excess pressure. The test disc has a pressure-measuring device with a microprocessor and a memory for recording and storing a pressure profile in the glove volume and a data interface. The glove and port have identification elements which are read by a reading device of the test disc and information concerning the pressure profile along with the identities of the glove and port are transmitted wirelessly to an evaluation unit which estimates and records a residual period of use of the glove. A plurality of gloves in ports can be tested simultaneously.