A system and method handles one or more pumping units in an out-of-balance condition. Sensing equipment monitors operating parameters related to balance of each of the one or more pumping units. Processing equipment determines the out-of-balance condition in at least one of the one or more pumping units based on the monitored operating parameters. A first correction to a counterbalance parameter of the at least one pumping unit can be calculated, such as a new position or weight of the counterbalance, so the out-of-balance condition can be corrected by implementing the new position or weight at the at least one pumping unit. A second correction to a stroke parameter of the at least one pumping unit can be calculated, such as a new stroke rate or pattern, so operation of the pumping unit can be maintained despite the out-of-balance condition.