- 专利标题: CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS
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申请号: US16032799申请日: 2018-07-11
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公开(公告)号: US20190016671A1公开(公告)日: 2019-01-17
- 发明人: Nadia AHMAD , Corey ANDERSON , Vijayalaksmi ARUMUGAM , Iuliana Luci ASGIAN , Joanne Louise CAMP , Lev Tyler Dewey FANNING , Sara Sabina HADIDA RUAH , Dennis HURLEY , Yvonne SCHMIDT , David SHAW , Urvi Jagdishbhai SHETH , Stephen Andrew THOMSON
- 申请人: VERTEX PHARMACEUTICALS INCORPORATED
- 主分类号: C07C235/64
- IPC分类号: C07C235/64 ; C07D213/81 ; C07D213/89 ; C07D239/34 ; C07D317/46 ; C07D405/12 ; C07D213/69 ; C07D213/82 ; C07D307/79
摘要:
Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
公开/授权文献
- US10647661B2 Carboxamides as modulators of sodium channels 公开/授权日:2020-05-12
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