- 专利标题： COMPOUNDS, COMPOSITIONS, AND METHODS FOR USING HLA-F
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申请号： US15546179申请日： 2016-01-20
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公开(公告)号： US20190038774A1公开(公告)日： 2019-02-07
- 发明人: Brian KASPAR
- 申请人： The Research Institute at Nationwide Children's Hospital
- 申请人地址： US OH Columbus
- 专利权人： The Research Institute at Nationwide Children's Hospital
- 当前专利权人： The Research Institute at Nationwide Children's Hospital
- 当前专利权人地址： US OH Columbus
- 国际申请： PCT/US16/14121 WO 20160120
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61P25/28
摘要：
The invention relates to compositions, compounds, methods, and uses for the treatment of amyotrophic lateral sclerosis. In particular, the invention relates to compounds, compositions, methods, and uses for the treatment of amyotrophic lateral sclerosis by increasing the expression of the MHC class I molecule, HLA-F, in motor neurons of the patient.
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