Invention Application
- Patent Title: FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB
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Application No.: US16136876Application Date: 2018-09-20
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Publication No.: US20190062445A1Publication Date: 2019-02-28
- Inventor: Maria Jure-Kunkel , Laura J. Hefta , Marc Santoro , Subinay Ganguly , Edward L. Halk
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00 ; C07K16/30 ; A61K39/39 ; A61K39/12
Abstract:
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
Information query
