- 专利标题: BODIPY DYES FOR BIOLOGICAL IMAGING
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申请号: US16017638申请日: 2018-06-25
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公开(公告)号: US20190127394A1公开(公告)日: 2019-05-02
- 发明人: Ralph Mazitschek , Alexandra M. Courtis , James Adam Hendricks
- 申请人: The General Hospital Corporation
- 主分类号: C07F5/02
- IPC分类号: C07F5/02 ; C07D257/08 ; A61K51/04 ; G01N33/534
摘要:
This invention relates to water-soluble mono-alkoxy and mono-alkyne BODIPY derivatives, including methods for making the same. For examples, provided herein are compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: is a BODIPY ligand system; X is a halogen; L is absent or a linker; and Z is selected from the group consisting of: a group reactive with a biologically active molecule and a detectable agent.
公开/授权文献
- US10696695B2 BODIPY dyes for biological imaging 公开/授权日:2020-06-30