- 专利标题： Activated Lactobacillus Reuteri Strains for Selective Pathogen Inhibition in a Human Microbial Community
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申请号： US16095284申请日： 2017-11-07
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公开(公告)号： US20190134115A1公开(公告)日： 2019-05-09
- 发明人: Stephan Roos , Jennifer Kristine Spinler
- 申请人： BioGaia AB
- 申请人地址： SE 64 Stockholm
- 专利权人： BioGaia AB
- 当前专利权人： BioGaia AB
- 当前专利权人地址： SE 64 Stockholm
- 优先权： SE1651459-8 20161107
- 国际申请： PCT/EP2017/078463 WO 20171107
- 主分类号： A61K35/747
- IPC分类号： A61K35/747 ; A01N63/02 ; A61P31/04 ; C12N1/04
摘要：
Herein is disclosed a probiotic composition comprising cells of Lactobacillus reuteri preloaded with reuterin for use in the treatment or prevention of an infection caused by Clostridium difficile and/or other glycerol metabolizing pathogen(s) in an individual, and a method for the treatment or prevention of an infection caused by Clostridium difficile and/or other glycerol metabolizing pathogen(s) in an individual. Further provided is a method for manufacturing a composition comprising L. reuteri pre-loaded with reuterin, and compositions obtained by said method.)
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