- 专利标题: ASPROSIN, A FAST-INDUCED GLUCOGENIC PROTEIN HORMONE
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申请号: US16092653申请日: 2017-04-13
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公开(公告)号: US20190144536A1公开(公告)日: 2019-05-16
- 发明人: Atul Chopra , David D. Moore
- 申请人: Baylor College of Medicine
- 国际申请: PCT/US17/27467 WO 20170413
- 主分类号: C07K16/26
- IPC分类号: C07K16/26 ; A61P3/04 ; G01N33/74
摘要:
Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.