- 专利标题： PIPERIDINES AS MENIN INHIBITORS
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申请号： US16098147申请日： 2017-05-02
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公开(公告)号： US20190152947A1公开(公告)日： 2019-05-23
- 发明人: Shaomeng Wang , Angelo Aguilar , Ke Zheng , Shilin Xu , Tianfeng Xu , Denzil Bernard , Liyue Huang
- 申请人： THE REGENTS OF THE UNIVERSITY OF MICHIGAN
- 国际申请： PCT/US2017/030577 WO 20170502
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61P35/00 ; C07D401/04 ; C07D405/04 ; C07D211/34
摘要：
The present disclosure provides compounds by Formula (I): (Formula(I)) and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R2, R3a, R3b, A, G, X, and Y are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to menin inhibition such as cancer.
公开/授权文献
- US10899738B2 Piperidines as menin inhibitors 公开/授权日：2021-01-26
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