发明申请
- 专利标题： SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS
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申请号： US16162887申请日： 2018-10-17
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公开(公告)号： US20190152974A1公开(公告)日： 2019-05-23
- 发明人: Piet André Maurits Maria HERDEWIJN , Steven Cesar Alfons DE JONGHE , William John WATKINS , Lee Shun CHONG
- 申请人： Gilead Sciences, Inc.
- 主分类号： C07D475/02
- IPC分类号： C07D475/02 ; C07D475/08 ; C07D475/00 ; C07D475/04 ; C07D475/06
摘要：
The invention provides 4,6-di- and 2,4,6-tri-substituted pteridine derivatives with a specific substitution pattern which exhibit a significant and selective activity against certain types of viral infections, in particular selectively inhibit replication of Flaviridae such as the hepatitis C virus, and are useful for the prevention and treatment of such viral infections.
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