Disclosed are a method, apparatus, and system for predicting a spread of a disaster with respect to multiple disasters. According to the present disclosure, the method includes: receiving disaster-related information; generating a disaster-connection scenario by applying a regional characteristic and connection between disasters to the disaster-related information; performing disaster modeling on each of the disasters that make up the disaster-connection scenario; and predicting a spread of the multiple disasters by integrating results of the disaster modeling. According to an embodiment of the present disclosure, it is possible that a spread of multiple disasters originated from a single disaster situation is predicted and provided in real time. Also, according to an embodiment of the present disclosure, it is possible that a multi-disaster situation predicted in real time is checked and preparation for natural disasters and multiple disasters in advance is performed.