- 专利标题： NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH
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申请号： US16213564申请日： 2018-12-07
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公开(公告)号： US20190183865A1公开(公告)日： 2019-06-20
- 发明人: Tomasz Cierpicki , Jolanta Grembecka , Huang Huang , Sergi Zari , Hyo Je Cho , Mykhaylo Potopnyk , Sergeii Dudkin , Wenbing Chen , Yassir Adam , Christina Howard , EunGi Kim
- 申请人： The Regents of the University of Michigan
- 主分类号： A61K31/428
- IPC分类号： A61K31/428 ; A61P35/00
摘要：
Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.
公开/授权文献
- US11324729B2 NSD family inhibitors and methods of treatment therewith 公开/授权日：2022-05-10
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