Invention Application
- Patent Title: SUBSTITUTED CYCLOHEXANES AS MUSCARINIC M1 RECEPTOR AND/OR M4 RECEPTOR AGONISTS
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Application No.: US16295364Application Date: 2019-03-07
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Publication No.: US20190202783A1Publication Date: 2019-07-04
- Inventor: Giles Albert Brown , Miles Stuart Congreve , Mark Pickworth , Benjamin Gerald Tehan
- Applicant: Heptares Therapeutics Limited
- Main IPC: C07D207/14
- IPC: C07D207/14 ; C07D487/10 ; C07D209/96 ; C07D271/06 ; C07D413/12 ; C07D487/04 ; C07D471/04 ; C07D413/14 ; C07D409/08 ; C07D243/08 ; C07D471/10 ; C07D403/04 ; C07D401/08 ; C07D213/57 ; C07D295/205 ; C07D413/04
Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor or M1 and M4 receptors and which are useful in the treatment of muscarinic M1 or M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula wherein Q4, Q5, R5, p, V, Q1, Q2, X1, X2 and W are defined herein.
Public/Granted literature
- US10759751B2 Substituted spirocyclohexanes as muscarinic M1 receptor and/or M4 receptor agonists Public/Granted day:2020-09-01
Information query
