发明申请
- 专利标题： C17, C20, AND C21 SUBSTITUTED NEUROACTIVE STEROIDS AND THEIR METHODS OF USE
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申请号： US16316853申请日： 2017-07-11
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公开(公告)号： US20190248831A1公开(公告)日： 2019-08-15
- 发明人: Albert Jean ROBICHAUD , Gabriel MARTINEZ BOTELLA , Boyd L. HARRISON , Francesco G. SALITURO , Andrew GRIFFIN , Maria Jesus BLANCO-PILLADO
- 申请人： SAGE THERAPEUTICS, INC.
- 申请人地址： US MA Cambridge
- 专利权人： Sage Therapeutics, Inc.
- 当前专利权人： Sage Therapeutics, Inc.
- 当前专利权人地址： US MA Cambridge
- 国际申请： PCT/US2017/041600 WO 20170711
- 主分类号： C07J41/00
- IPC分类号： C07J41/00 ; C07J43/00 ; C07J1/00 ; A61P25/20 ; A61P25/08 ; A61P25/28 ; A61P5/00 ; A61P25/18
摘要：
Described herein are neuroactive steroids or a pharmaceutically acceptable salt thereof. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. Also provided are pharmaceutical compositions comprising a compound described herein and methods of use and treatment, e.g., such as for inducing sedation and/or anesthesia.