Invention Application
- Patent Title: GLS1 INHIBITORS FOR TREATING DISEASE
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Application No.: US16412050Application Date: 2019-05-14
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Publication No.: US20190270736A1Publication Date: 2019-09-05
- Inventor: Maria Emilia DI FRANCESCO , Philip JONES , Timothy HEFFERNAN , Matthew M. HAMILTON , Zhijun KANG , Michael J. SOTH , Jason P. BURKE , Kang LE , Christopher Lawrence CARROLL , Wylie S. PALMER , Richard LEWIS , Timothy MCAFOOS , Barbara CZAKO , Gang LIU , Jay THEROFF , Zachary HERRERA , Anne YAU
- Applicant: Board of Regents, The University of Texas System
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61K31/497 ; C07D493/08 ; A61K31/444 ; C07D403/14 ; C07D405/14 ; A61K31/4192 ; A61K31/4439 ; C07D401/14 ; A61K31/501 ; C07D403/06 ; A61K31/433 ; C07D417/06 ; A61K45/06 ; A61K31/454
Abstract:
Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
Public/Granted literature
- US10766892B2 GLS1 inhibitors for treating disease Public/Granted day:2020-09-08
Information query
