- 专利标题： TETRACYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS
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申请号： US16447271申请日： 2019-06-20
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公开(公告)号： US20190315769A1公开(公告)日： 2019-10-17
- 发明人: Thomas H. Graham , Tao Yu , Yonglian Zhang , John A. McCauley
- 申请人： MERCK SHARP & DOHME CORP.
- 申请人地址： US NJ Rahway
- 专利权人： MERCK SHARP & DOHME CORP.
- 当前专利权人： MERCK SHARP & DOHME CORP.
- 当前专利权人地址： US NJ Rahway
- 主分类号： C07D498/22
- IPC分类号： C07D498/22 ; A61P31/18 ; C07D498/16 ; C07D487/16 ; A61K31/553 ; A61K31/4188 ; A61K31/407 ; A61K31/5365 ; A61K31/4985 ; C07D471/22
摘要：
The present invention relates to Tetracyclic Heterocycle Compounds of Formula and pharmaceutically acceptable salts or prodrug thereof, wherein A, X, R1, R2, R3 and R7 are as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Heterocycle Compound, and methods of using the Tetracyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.
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