Invention Application
- Patent Title: SUBSTITUTED QUINOLIZINE DERIVATIVES USEFUL AS HIV INTEGRASE INHIBITORS
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Application No.: US16479997Application Date: 2018-01-23
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Publication No.: US20190365727A1Publication Date: 2019-12-05
- Inventor: Tao Yu , John A. McCauley , Alan Whitehead , James M. Apgar , Izzat T. Raheem , Guizhen Dong , Sherman T. Waddell , Hong Li
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee Address: US NJ Rahway
- International Application: PCT/US2018/014761 WO 20180123
- Main IPC: A61K31/4375
- IPC: A61K31/4375 ; C07D491/147 ; A61K31/5365 ; A61K31/506 ; A61K31/7068 ; A61K31/7076 ; A61K31/427 ; A61K31/4402 ; A61K31/675 ; A61K31/47
Abstract:
The present invention relates to Substituted Quinolizine Derivatives of Formula (I): and pharmaceutically acceptable salts thereof, wherein R1 is as defined herein. The present invention also relates to compositions comprising at least one Substituted Quinolizine Derivative, and methods of using the Substituted Quinolizine Derivatives for treating or preventing HIV infection in a subject.
Public/Granted literature
- US10786488B2 Substituted quinolizine derivatives useful as HIV integrase inhibitors Public/Granted day:2020-09-29
Information query
IPC分类:
