Invention Application
- Patent Title: BCMA CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
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Application No.: US16439495Application Date: 2019-06-12
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Publication No.: US20190382500A1Publication Date: 2019-12-19
- Inventor: Aida Abujoub , John Blankenship , Dexiu Bu , Tony Fleming , Brian Holmberg , Connie Hong , Lu Huang , Chonghui Zhang
- Applicant: Novartis AG
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/725 ; C07K14/705 ; C12N5/0783 ; A61P35/00 ; A61K35/17
Abstract:
The invention provides compositions and methods for treating diseases associated with expression of BCMA. The invention also relates to chimeric antigen receptor (CAR) specific to BCMA, vectors encoding the same, and recombinant T cells comprising the BCMA CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a BCMA binding domain.
Public/Granted literature
- US11608382B2 BCMA chimeric antigen receptors and uses thereof Public/Granted day:2023-03-21
Information query
