- 专利标题: ETHANE-SULFONATE SALT OF QUINOLINE DERIVATIVE
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申请号: US16480514申请日: 2018-01-25
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公开(公告)号: US20190389837A1公开(公告)日: 2019-12-26
- 发明人: Takahiro NEKADO , Hideomi KIJIMA , Shizuka ONO , Toshihiko NISHIYAMA
- 申请人: ONO PHARMACEUTICAL CO., LTD.
- 申请人地址: JP Osaka-shi
- 专利权人: ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人: ONO PHARMACEUTICAL CO., LTD.
- 当前专利权人地址: JP Osaka-shi
- 优先权: JP2017-011835 20170126
- 国际申请: PCT/JP2018/002250 WO 20180125
- 主分类号: C07D401/14
- IPC分类号: C07D401/14
摘要:
The present invention relates to an ethane-sulfonate salt of N-{5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl}-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide, which has an Axl-inhibiting activity and is useful as a prophylactic and/or therapeutic agent for immune diseases, cancer and the like, a crystal thereof, and a pharmaceutical composition thereof.
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