发明申请
- 专利标题: PROCESSES FOR PREPARING JAK INHIBITORS AND RELATED INTERMEDIATE COMPOUNDS
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申请号: US16436195申请日: 2019-06-10
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公开(公告)号: US20200002341A1公开(公告)日: 2020-01-02
- 发明人: Jiacheng Zhou , James D. Rodgers , Haisheng Wang
- 申请人: Incyte Holdings Corporation , Incyte Corporation
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07F7/18 ; C07F7/10 ; C07F5/02 ; C07F7/08
摘要:
The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.
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