- 专利标题： Thienopyridine Carboxamides as Ubiquitin-Specific Protease Inhibitors
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申请号： US16077407申请日： 2017-02-13
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公开(公告)号： US20200017525A1公开(公告)日： 2020-01-16
- 发明人: David Joseph Guerin , Kenneth W. Bair , Justin A. Caravella , Stephanos Ioannidis, Jr. , David R. Lancia, Jr. , Hongbin Li , Steven Mischke , Pui Yee Ng , David Richard , Shawn E.R. Schiller , Tatiana Shelekhin , Zhongguo Wang
- 申请人： FORMA Therapeutics, Inc.
- 国际申请： PCT/US2017/017690 WO 20170213
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; C07D495/04
摘要：
The disclosure relates to inhibitors of USP28 and/or USP25 useful in the treatment of cancers, inflammation, autoimmune diseases, and infectious diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, R6, R7, X, m, and n are described herein.
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