Methods of conducting object-related procedures and associated system involve a secure and physical interaction being formed between a fiducial device and a site having an associated object to form a fiducial marker. A virtual plan is formed, detailing the procedure on the object at the site, in registration with and with respect to the fiducial marker. Movement of a procedure-conducting device is physically regulated with a guidance device responsive to a controller device and with respect to the fiducial marker. The guidance device physically regulates movement of the procedure-conducting device, according to the virtual plan and corresponding with physical manipulation of the procedure-conducting device by the user, to conduct the procedure. Tactile feedback is provided to the user, via the procedure-conducting device, if the physical manipulation by the user causes the procedure-conducting device to deviate from the virtual plan.