Embodiments of systems and methods for on-screen keyboard detection for multi-form factor Information Handling Systems (IHSs) are described. In an illustrative, non-limiting embodiment, an IHS may include a processor; and a memory coupled to the processor, the memory having program instructions stored thereon that, upon execution by the processor, cause the IHS to: detect a keyboard using a magnetic sensor; and determine, in response to the detection, a position of the keyboard relative to a display surface of a second display, where the second display is coupled to a first display via a hinge.