Invention Application
- Patent Title: INDOLE CARBOXAMIDE COMPOUNDS
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Application No.: US16774202Application Date: 2020-01-28
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Publication No.: US20200165222A1Publication Date: 2020-05-28
- Inventor: Qingjie LIU , Scott Hunter Watterson , John E. Macor , Khehyong Ngu , Saleem Ahmad
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Main IPC: C07D401/10
- IPC: C07D401/10 ; C07D209/08 ; A61P37/00 ; A61P29/00 ; C07D209/18 ; C07D487/10 ; C07D487/04 ; C07D471/04 ; C07D417/04 ; C07D413/04 ; C07D403/10 ; C07D403/04 ; C07D401/12 ; C07D401/06 ; C07D401/04 ; C07D403/12

Abstract:
Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR4 or N; R1, R2, R3, R4, and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
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