- 专利标题： ENGINEERED SUBSTRATES FOR HIGH-THROUGHPUT GENERATION OF 3D MODELS OF TUMOR DORMANCY, RELAPSE AND MICROMETASTASES FOR PHENOTYPE SPECIFIC DRUG DISCOVERY AND DEVELOPMENT
-
申请号： US16708027申请日： 2019-12-09
-
公开(公告)号： US20200165572A1公开(公告)日： 2020-05-28
- 发明人: Kaushal Rege , Taraka Sai Pavan Grandhi , Thrimoorthy Potta
- 申请人： Kaushal Rege , Taraka Sai Pavan Grandhi , Thrimoorthy Potta
- 申请人地址： US AZ Scottsdale
- 专利权人： Arizona Board of Regents on behalf of Arizona State University
- 当前专利权人： Arizona Board of Regents on behalf of Arizona State University
- 当前专利权人地址： US AZ Scottsdale
- 主分类号： C12N5/09
- IPC分类号： C12N5/09 ; G01N33/50 ; C12N5/00 ; C08J3/075
摘要：
Methods to form a novel aminoglycoside based hydrogel for high-throughput generation of 3D dormant, relapsed and micrometastatic tumor microenvironments are disclosed. In addition, methods of screening agents against tumor cells grown in the 3D environments disclosed herein that include, for example, screening of lead drugs and therapies for an effect on dormant, relapsed and/or micrometastatic tumor cells.
公开/授权文献
- US1769299A Inkwell 公开/授权日：1930-07-01
信息查询
