Invention Application
- Patent Title: ENGINEERED SUBSTRATES FOR HIGH-THROUGHPUT GENERATION OF 3D MODELS OF TUMOR DORMANCY, RELAPSE AND MICROMETASTASES FOR PHENOTYPE SPECIFIC DRUG DISCOVERY AND DEVELOPMENT
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Application No.: US16708027Application Date: 2019-12-09
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Publication No.: US20200165572A1Publication Date: 2020-05-28
- Inventor: Kaushal Rege , Taraka Sai Pavan Grandhi , Thrimoorthy Potta
- Applicant: Kaushal Rege , Taraka Sai Pavan Grandhi , Thrimoorthy Potta
- Applicant Address: US AZ Scottsdale
- Assignee: Arizona Board of Regents on behalf of Arizona State University
- Current Assignee: Arizona Board of Regents on behalf of Arizona State University
- Current Assignee Address: US AZ Scottsdale
- Main IPC: C12N5/09
- IPC: C12N5/09 ; G01N33/50 ; C12N5/00 ; C08J3/075
Abstract:
Methods to form a novel aminoglycoside based hydrogel for high-throughput generation of 3D dormant, relapsed and micrometastatic tumor microenvironments are disclosed. In addition, methods of screening agents against tumor cells grown in the 3D environments disclosed herein that include, for example, screening of lead drugs and therapies for an effect on dormant, relapsed and/or micrometastatic tumor cells.
Public/Granted literature
- US1769299A Inkwell Public/Granted day:1930-07-01
Information query
