Invention Application
![2-[4-(METHYLAMINOMETHYL)PHENYL]-5-FLUORO-BENZOFURAN-7-CARBOXAMIDE HYDROCHLORIDE POLYMORPH, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF](/docs/US/2020-06-04/US20200172502A1/abs.jpg.600x600.jpg)
- Patent Title: 2-[4-(METHYLAMINOMETHYL)PHENYL]-5-FLUORO-BENZOFURAN-7-CARBOXAMIDE HYDROCHLORIDE POLYMORPH, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
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Application No.: US16623297Application Date: 2018-05-31
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Publication No.: US20200172502A1Publication Date: 2020-06-04
- Inventor: Chunhao YANG , Zehong MIAO , Cun TAN , Xiajuan HUAN , Jian DING , Yi CHEN
- Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES , FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@57eeedfb
- International Application: PCT/CN2018/089222 WO 20180531
- Main IPC: C07D307/84
- IPC: C07D307/84
![2-[4-(METHYLAMINOMETHYL)PHENYL]-5-FLUORO-BENZOFURAN-7-CARBOXAMIDE HYDROCHLORIDE POLYMORPH, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF](/abs-image/US/2020/06/04/US20200172502A1/abs.jpg.150x150.jpg)
Abstract:
Disclosed are a 2-[4-(methylaminomethyl)phenyl]-5-fluoro-benzofuran-7-carboxamide hydrochloride polymorph, a preparation method therefor and an application thereof. Specifically, disclosed are three crystalline forms, i.e., crystalline forms A, B, and C, of 2-[4-(methylaminomethyl)phenyl]-5-fluoro-benzofuran-7-carboxamide hydrochloride (formula I), preparation methods for the three crystalline forms, and use of the three crystalline forms in preparation of drugs.
Public/Granted literature
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