A mouse having a movable lighting structure includes a mouse body, the movable lighting structure, a lighting module and a wire. The mouse body has a longitudinal axis defining a longitudinal axis direction, and has a top surface and a bottom surface opposite to each other. The movable lighting structure is movably disposed on the mouse body, and has an accommodating space formed therein. The lighting module is disposed in the accommodating space, and has at least one light-emitting element. The wire is connected between the mouse body and the lighting module for supplying power required by the lighting module.