- 专利标题： NOVEL SUBSTITUTED N'-HYDROXYCARBAMIMIDOYL-1,2,5-OXADIAZOLE COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS
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申请号： US16326408申请日： 2017-08-24
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公开(公告)号： US20200231606A1公开(公告)日： 2020-07-23
- 发明人: Kun Liu , Abdelghani Achab , Purakkattle Biju , Timothy A. Cernak , Yongqi Deng , Xavier Fradera , Liangqin Guo , Yongxin Han , Shuwen He , Joseph Kozlowski , Derun Li , Guoqing Li , Qinglin Pu , Zhi-Cai Shi , Wensheng Yu , Hongjun Zhang
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 国际申请： PCT/US2017/048314 WO 20170824
- 主分类号： C07F5/02
- IPC分类号： C07F5/02 ; C07D271/08 ; C07D413/12
摘要：
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Formula (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.