- 专利标题： EBNA1 INHIBITORS AND METHODS USING SAME
-
申请号： US16571896申请日： 2019-09-16
-
公开(公告)号： US20200239415A1公开(公告)日： 2020-07-30
- 发明人: Troy E. Messick , Garry R. Smith , Allen B. Reitz , Paul M. Lieberman , Mark E. McDonnell , Yan Zhang , Marianne Carlsen , Shuai Chen
- 申请人： THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
- 主分类号： C07D209/08
- IPC分类号： C07D209/08 ; A61K31/422 ; C07D401/10 ; C07D471/04 ; A61K31/541 ; A61K31/437 ; A61K31/41 ; A61K31/501 ; A61K31/427 ; C07D403/14 ; C07D277/62 ; A61K31/4155 ; A61K31/519 ; C07D417/10 ; A61K31/551 ; A61K31/496 ; C07D403/12 ; A61K31/4375 ; C07D401/12 ; C07D413/10 ; A61K45/06 ; A61K31/4725 ; C07D417/12 ; C07D491/107 ; A61K31/4439 ; C07D403/10 ; C07D401/14 ; C07D487/04 ; A61K31/435 ; A61K31/404 ; A61K31/5377 ; A61K31/506 ; A61K31/454 ; A61P35/00 ; C07D471/08 ; A61K31/517 ; C07D471/10 ; A61P31/20 ; A61K31/433 ; C07D409/12 ; C07D487/08 ; A61K31/426 ; C07D405/12 ; C07D405/14
摘要：
The present invention provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection.
公开/授权文献
- US10981867B2 EBNA1 inhibitors and methods using same 公开/授权日：2021-04-20
信息查询
