A wireless device receives one or more messages comprising configuration parameters. The configuration parameters indicate pathloss reference signals (RSs) for PUSCH pathloss estimation for transmissions via first and second panels. A medium access control control element (MAC CE) is received. The MAC CE indicates first pathloss RSs of the plurality of pathloss RSs for the first panel. The MAC CE indicates second pathloss RSs of the plurality of pathloss RSs for the second panel. A downlink control information (DCI) is received. The DCI indicates a first pathloss RS. The DCI indicates a second pathloss RS. The wireless device transmits, via the first panel, a first uplink transport block with a first uplink transmission power determined based on the first pathloss RS. The wireless device transmits, via the second panel, a second uplink transport block with a second uplink transmission power determined based on the second pathloss RS.