- 专利标题： BIODEGRADABLE COMPOUND, LIPID PARTICLE, COMPOSITION COMPRISING LIPID PARTICLE, AND KIT
-
申请号： US16812625申请日： 2020-03-09
-
公开(公告)号： US20200270217A1公开(公告)日： 2020-08-27
- 发明人: Mitsuko ISHIHARA , Eiichi Akahoshi , Katsuyuki Naito , Emi Nozaki , Saeko Saruwatari
- 申请人： KABUSHIKI KAISHA TOSHIBA
- 申请人地址： JP Minato-ku
- 专利权人： KABUSHIKI KAISHA TOSHIBA
- 当前专利权人： KABUSHIKI KAISHA TOSHIBA
- 当前专利权人地址： JP Minato-ku
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3fee5534
- 主分类号： C07D243/08
- IPC分类号： C07D243/08 ; C07C229/30 ; C07D233/02 ; C07D241/04 ; C07D211/14 ; A61K9/127
摘要：
The present embodiment provides a compound represented by the formula (1): Q-CHR2 (1) (Q is a nitrogen-containing aliphatic group containing two or more tertiary nitrogens but no oxygen, and R is an aliphatic group containing a biodegradable group). From the compound in combination with other lipids such as a lipid capable of reducing aggregation, lipid particles can be formed. Further, the compound can be used for a pharmaceutical composition to deliver an activator into cells.