Invention Application
- Patent Title: T-TYPE CALCIUM CHANNEL INHIBITOR
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Application No.: US16650746Application Date: 2018-09-21
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Publication No.: US20200308132A1Publication Date: 2020-10-01
- Inventor: Atsufumi KAWABATA , Fumiko SEKIGUCHI , Maho TSUBOTA , Naoki TOYOOKA , Hiroyuki NISHIKAWA
- Applicant: KINKI UNIVERSITY , NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA , FUSO PHARMACEUTICAL INDUSTRIES, LTD.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@4e52b5ef
- International Application: PCT/JP2018/035170 WO 20180921
- Main IPC: C07D311/32
- IPC: C07D311/32 ; A61P23/00

Abstract:
A new analgesic has been developed for T-type calcium channels as therapeutic targets.The present invention provides a T-type calcium channel inhibitor which is a compound represented by formula (1): wherein each of R1 and R2 independently represents —H or —OH; R3 represents —OH; R4 represents —OH or —H; R5 represents a straight or branched alkyl or cycloalkyl-alkyl group having one to ten carbon atoms or a straight or branched alkenyl or cycloalkyl-alkenyl group having two to ten carbon atoms, or a pharmaceutically acceptable salt or solvate thereof. The present invention also provides this T-type calcium channel inhibitor, a medicament containing the T-type calcium channel inhibitor, and a therapeutic or prophylactic agent for a disease having an effective T-type calcium channel inhibitory action.
Public/Granted literature
- US11479537B2 T-type calcium channel inhibitor Public/Granted day:2022-10-25
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