- 专利标题： CONSTRUCTS TRAGETING CD22 AND USES THEREOF
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申请号： US17043352申请日： 2019-03-29
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公开(公告)号： US20210017280A1公开(公告)日： 2021-01-21
- 发明人: Jun CUI , Pengbo Zhang , Yiyang Xu , Shan Li , Yixiang Xu , Guangyan Xiong , Hongruo Yun , Lianxing Liu , Xiaomei Ge , Shaohua Xu , Hong Liu , Javier Morales
- 申请人： Eureka Therapeutics, Inc.
- 申请人地址： US CA Emeryville
- 专利权人： Eureka Therapeutics, Inc.
- 当前专利权人： Eureka Therapeutics, Inc.
- 当前专利权人地址： US CA Emeryville
- 国际申请： PCT/US2019/025032 WO 20190329
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K14/725 ; G01N33/574 ; A61P35/00
摘要：
Described herein are antibodies (e.g., single chain variable fragment (scFv) antibodies) and constructs comprising antibody moieties that bind to the extracellular domain of CD22 or a portion thereof (e.g., SEQ ID NO: 205 or a portion thereof). Also provided herein are methods of using the same or compositions thereof for the therapeutic treatment of diseases characterized by CD22 expression, in particular, B-cell lymphomas and leukemias.
公开/授权文献
- US11827672B2 Constructs trageting CD22 and uses thereof 公开/授权日：2023-11-28
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