- 专利标题: TRIAZOLOPYRIMIDINES, THEIR PREPARATION AND USE
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申请号: US17085791申请日: 2020-10-30
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公开(公告)号: US20210047337A1公开(公告)日: 2021-02-18
- 发明人: Konstantin Petrukhin , Kirsten Alison Rinderspacher , Shi-Xian Deng , Andras Varadi , Boglarka Racz , Peter Bernstein , Patricia C. Weber , Donald W. Landry , Andrew S. Wasmuth
- 申请人: Konstantin Petrukhin , Kirsten Alison Rinderspacher , Shi-Xian Deng , Andras Varadi , Boglarka Racz , Peter Bernstein , Patricia C. Weber , Donald W. Landry , Andrew S. Wasmuth
- 申请人地址: US NY New Windsor; US NY Mount Vernon; US NY White Plains; US NY New York; US NY New York; US PA Philadelphia; US PA Yardley; US NY New York; US NY Brooklyn
- 专利权人: Konstantin Petrukhin,Kirsten Alison Rinderspacher,Shi-Xian Deng,Andras Varadi,Boglarka Racz,Peter Bernstein,Patricia C. Weber,Donald W. Landry,Andrew S. Wasmuth
- 当前专利权人: Konstantin Petrukhin,Kirsten Alison Rinderspacher,Shi-Xian Deng,Andras Varadi,Boglarka Racz,Peter Bernstein,Patricia C. Weber,Donald W. Landry,Andrew S. Wasmuth
- 当前专利权人地址: US NY New Windsor; US NY Mount Vernon; US NY White Plains; US NY New York; US NY New York; US PA Philadelphia; US PA Yardley; US NY New York; US NY Brooklyn
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D519/00 ; A61P27/02
摘要:
The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3, C1-C4 alkyl, aryl or heteroaryl; X is N or CR6, wherein R6 is H, OH, or halogen; A is absent or present, and when present is B has the structure: or a pharmaceutically acceptable salt thereof.
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