An apparatus for protecting a device of a motor drive inverter includes a plurality of power modules configured to control the multi-phase alternating current supplied to the motor. Each of the plurality of power modules includes a top phase switching device connected to a positive terminal of the battery, a bottom phase switching device connected in series to the top phase switching device and connected to a negative terminal of the battery, and a current interruption unit connected in series to the top phase switching device and the bottom phase switching device, and configured to be disconnected when a current greater than or equal to a desired interrupting current flows thereto, so as to prevent a switching device of a power module from being burned out due to an overcurrent by installing a fuse wire to the power module.