- 专利标题： HETERODUPLEX NUCLEIC ACID MOLECULES AND USES THEREOF
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申请号： US16960543申请日： 2019-01-03
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公开(公告)号： US20210095283A1公开(公告)日： 2021-04-01
- 发明人: Andrew John GEALL , Venkata Ramana DOPPALAPUDI , Rachel Elizabeth JOHNS , Rob BURKE , David Sai-Ho CHU , Michael Caramian COCHRAN , Michael David HOOD , Hanhua HUANG
- 申请人： Avidity Biosciences, Inc.
- 申请人地址： US CA La Jolla
- 专利权人： Avidity Biosciences, Inc.
- 当前专利权人： Avidity Biosciences, Inc.
- 当前专利权人地址： US CA La Jolla
- 国际申请： PCT/US19/12223 WO 20190103
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; C07K16/28
摘要：
Disclosed herein are heteroduplex nucleic acid molecules, heteroduplex nucleic acid conjugates, and pharmaceutical compositions for modulating a protein expression. Also described herein include methods of treating a disease or indication which utilize a heteroduplex nucleic acid molecule, a heteroduplex nucleic acid conjugate, or a pharmaceutical composition that comprises a heteroduplex nucleic acid molecule.
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