- 专利标题： ANTI-ALPHA SYNUCLEIN ANTIBODIES
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申请号： US16772043申请日： 2018-12-13
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公开(公告)号： US20210101964A1公开(公告)日： 2021-04-08
- 发明人: Patrick DOWNEY , Kerry Louise TYSON , Marco KRIEK , Lorenzo DE LICHTERVELDE , Daniel John LIGHTWOOD , David James MCMILLAN , Peter Charles ELLIOTT , Terence Seward BAKER
- 申请人： UCB Biopharma SRL
- 申请人地址： BE Brussels
- 专利权人： UCB Biopharma SRL
- 当前专利权人： UCB Biopharma SRL
- 当前专利权人地址： BE Brussels
- 优先权： GB1720970.1 20171215
- 国际申请： PCT/EP2018/084689 WO 20181213
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; A61P25/16
摘要：
The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.
公开/授权文献
- US11292831B2 Anti-alpha synuclein antibodies 公开/授权日：2022-04-05
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