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公开(公告)号:US20210107971A1
公开(公告)日:2021-04-15
申请号:US16771993
申请日:2018-12-13
申请人: UCB Biopharma SRL
发明人: Ralph ADAMS , Patrick DOWNEY , Terence Seward BAKER , Kerry Louise TYSON , Lorenzo DE LICHTERVELDE , Daniel John LIGHTWOOD , David James MCMILLAN
IPC分类号: C07K16/18
摘要: The present invention relates to antibodies binding alpha synuclein and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.
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公开(公告)号:US20220340648A1
公开(公告)日:2022-10-27
申请号:US17682082
申请日:2022-02-28
申请人: UCB Biopharma SRL
发明人: Patrick DOWNEY , Kerry Louise TYSON , Marco KRIEK , Lorenzo DE LICHTERVELDE , Daniel John LIGHTWOOD , David James MCMILLAN , Peter Charles ELLIOT , Terence Seward BAKER
摘要: The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.
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公开(公告)号:US20220220192A1
公开(公告)日:2022-07-14
申请号:US17585174
申请日:2022-01-26
申请人: UCB BIOPHARMA SRL
发明人: Ralph ADAMS , Patrick DOWNEY , Terence Seward BAKER , Kerry Louise TYSON , Lorenzo DE LICHTERVELDE , Daniel John LIGHTWOOD , David James MCMILLAN
IPC分类号: C07K16/18
摘要: The present invention relates to antibodies binding alpha synuclein and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.
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公开(公告)号:US20210101964A1
公开(公告)日:2021-04-08
申请号:US16772043
申请日:2018-12-13
申请人: UCB Biopharma SRL
发明人: Patrick DOWNEY , Kerry Louise TYSON , Marco KRIEK , Lorenzo DE LICHTERVELDE , Daniel John LIGHTWOOD , David James MCMILLAN , Peter Charles ELLIOTT , Terence Seward BAKER
摘要: The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.
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