- 专利标题: COMPOSITIONS AND METHODS FOR NUCLEIC ACID TRANSFER
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申请号: US17121835申请日: 2020-12-15
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公开(公告)号: US20210102208A1公开(公告)日: 2021-04-08
- 发明人: Assem G. Ziady , Matthew Siefert , Songbai Lin , Harrison Brown
- 申请人: Children's Hospital Medical Center
- 申请人地址: US OH Cincinnati
- 专利权人: Children's Hospital Medical Center
- 当前专利权人: Children's Hospital Medical Center
- 当前专利权人地址: US OH Cincinnati
- 主分类号: C12N15/113
- IPC分类号: C12N15/113 ; A61K38/17 ; A61K47/60 ; A61K47/64 ; A61K31/713 ; A61K31/395 ; A61K31/4709 ; A61K31/565 ; A61K31/132 ; A61K31/573 ; A61K31/352 ; A61K31/265 ; A61K31/05 ; A61K31/704 ; A61K31/519 ; A61K31/52 ; A61K31/7048 ; A61K48/00 ; A61K31/7088 ; C12N15/85 ; A61K45/06 ; C12N15/11
摘要:
Disclosed are methods for the enhancement of nucleic acid delivery systems. The methods may employ treatment with a compound and/or an RNAi molecule in combination with a nucleic acid to improve nucleic acid uptake into a cell. In particular, the disclosed methods may be useful for improved gene therapy techniques.
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